目的：了解肺动脉高压患者的生活质量状况并探讨其影响因素。方法：采用整群抽样的方法选择2014年6月至2015年6月期间在中南大学湘雅医院住院治疗的68例肺动脉高压患者作为研究对象。采用一般资料问卷、中文版简明健康调查量表(Short Form 36 Health Survey Questionnaire，SF-36)对其进行调查，运用单因素分析及多元线性回归法分析其影响因素。结果：肺动脉高压患者SF-36量表各维度评分均低于常模，差异均有统计学意义(P<0.05)。影响生活质量生理健康的因素为性别、6分钟步行试验距离(6-minute walking distance，6MWD)、是否合并右心衰竭、是否坚持氧疗；影响生活质量心理健康的因素为性别、文化程度、有无医疗保险。结论：肺动脉高压患者生活质量不高。医护人员应对女性、文化程度低、无医疗保险、6MWD短、合并右心衰竭、未坚持氧疗的患者给予更多的关注。
The quality of life and its influencing factors in patients with pulmonary arterial hypertension
Objective: To investigate the quality of life and its influencing factors in patients with pulmonary arterial hypertension. Methods: A total of 68 patients with pulmonary arterial hypertension who were in Xiangya Hospital of Central South University from June 2014 to June 2015 were selected in this study by cluster sampling. The general data questionnaire and the Short Form 36 Health Survey Questionnaire (SF-36) were used to evaluate the potential factors that affect the quality of life in patients with pulmonary arterial hypertension. The influencing factors of quality of life were analyzed by multiple linear regression analysis. Results: compared with the general population, all dimension score of SF-36 scale was lower in patients with pulmonary arterial hypertension (P<0.05). The influencing factors of physical component of quality of life were gender, the distance of 6-minute walking distance (6MWD), right heart failure or not, oxygen therapy or not, while the influencing factors of mental component of quality of life were gender, educational level and medical insurance or not. Conclusion: The quality of life in patients with pulmonary arterial hypertension was not optimistic. The medical workers should pay more attention to patients who are female self-pay with low educational level, right heart failure, short distance of 6MWT, or without oxygen therapy.