肾肉瘤样癌(sarcomatoid renal cell carcinoma，sRCC)是肾细胞癌(renal cell carcinoma，RCC)亚型的一种变异，不是一个单独的类型，它可以发生在任何肾细胞癌亚型。临床上讲，肾肉瘤样癌具有生长迅速、诊断时高转移率、对治疗反应差、预后差和较短总生存期的特点。由于对肾肉瘤样癌研究有限，导致在理解和治疗这种肿瘤方面进步微小。因为这个疾病占晚期疾病的10%~20%，占肾细胞癌死亡率的首位，所以肾肉瘤样癌是一个需要所有临床医生熟悉的重要疾病。
Research progress in renal sarcomatoid carcinoma
Sarcomatoid renal cell carcinomas (sRCC) are not considered a distinct subtype and can be recognized in association with every histologic type of renal cell carcinoma (RCC). Clinically, tumors with sarcomatoid changes carry a poor prognosis with rapid tumor growth, high rates of metastasis at the time of diagnosis, poor response to historical treatment, and shorter overall survival (OS). Limited research on tumors with sarcomatoid change has led to minimal progress in the understanding and treatment of these tumors. sRCC is an important entity for all clinicians to be familiar with. Because this entity may account for 10%~20% of patients with advanced disease, it continues to be a major contributor to RCC mortality.