论著 Original Article

局限型和广泛型侵袭性牙周炎的临床特点及预后研究

Published at: 2016年第36卷第5期

常静 1 , 马钧 1
1 北京市昌平区医院口腔科,北京 102200
通讯作者 静 常 Email: changjingxx@126.com
DOI: 10.3978/j.issn.2095-6959.2016.05.016
基金:

摘要

目的:观察局限型和广泛型侵袭性牙周炎患者的临床特点和治疗效果。方法:选取2014年5月至2015年5月在我科接受治疗的80例牙周炎患者为研究对象,其中局限型和广泛型侵袭性牙周炎患者各40例。观察不同类型牙周炎患者的临床特点及治疗效果,分析影响侵袭性牙周炎治疗效果的因素。结果:广泛型侵袭性牙周炎患者的菌斑百分率、出血指数和牙周袋深度明显高于局限型患者,差别具有统计学意义;广泛型侵袭性牙周炎患者的WBC、NEU%和炎症细胞因子(PCT、IL-6、hs-CRP和TNF-α)水平均明显高于局限型侵袭性牙周炎(P<0.05);局限型侵袭性牙周炎患者治疗的有效例数明显多于广泛型侵袭性牙周炎患者,无效例数明显少于广泛型侵袭性牙周炎患者;多因素Logistic回归分析结果显示,牙周炎类型、治疗前牙周状况、是否吸烟以及是否采用全身治疗是影响侵袭性牙周炎患者治疗的危险因素,其OR值分别为4.435、7.952、3.281、5.283。结论:广泛型侵袭性牙周炎患者的牙周状况和炎症相关实验室指标均较局限型侵袭性牙周炎差,且牙周炎类型、治疗前牙周状况、是否吸烟以及是否采用全身治疗是影响侵袭性牙周炎患者治疗效果的重要因素。


Clinical characteristics and prognosis of localized and extensive aggressive periodontitis

Abstract

Objective: To observe the clinical characteristics and treatment effect of the patients with localized and extensive aggressive periodontitis. Methods: Eighty patients with periodontitis treated in our department from May 2014 to May 2015 were selected for the study, and 40 cases of patients with localized and extensive aggressive periodontitis. Observed the clinical characteristics of patients with different types of periodontitis, and analyzed the factors affecting the therapeutic effect of aggressive periodontitis. Results: The percentage of plaque, bleeding index and periodontal pocket depth in extensive aggressive periodontitis patients were significantly higher than those in localized group. The levels of NEU%, WBC and inflammatory cytokines (IL-6, hs-CRP, PCT and TNF-α) were significantly higher than those in patients with extensive invasive periodontitis. Multiple Logistic regression analysis showed that the type of periodontitis, periodontal status, smoking, and whether the use of systemic therapy were the risk factors for the treatment of patients with aggressive periodontitis, the OR rate were 4.435, 7.952, 3.281, 5.283. Conclusion: The periodontal status and inflammation related laboratory index of the patients with extensive type of aggressive periodontitis were more limited than those of the localized type, and the type of periodontitis, periodontal status, smoking, and whether the use of systemic therapy are important factors in the treatment of patients with aggressive periodontitis.


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引用

引用本文: 静 常, 钧 马. 局限型和广泛型侵袭性牙周炎的临床特点及预后研究[J]. 临床与病理杂志, 2016, 36(5): 614-618.
Cite this article as: CHANG Jing, MA Jun . Clinical characteristics and prognosis of localized and extensive aggressive periodontitis[J]. Journal of Clinical and Pathological Research, 2016, 36(5): 614-618.