目的：观察开角型青光眼(primary open angle glaucoma，POAG)与开角型青光眼合并糖尿病患者小梁切除术后脉络膜厚度的变化。方法：选择在我院眼科住院治疗的开角型青光眼患者120例 (130只眼)为研究对象，根据是否合并有糖尿病分为青光眼组69例(76只眼)和合并糖尿病组51例(54只眼)，应用光学相干断层扫描技术(optical coherence tomography，OCT)于小梁切除术前后对视网膜色素上皮层到内巩膜层的垂直距离(即脉络膜厚度)进行测量。通过软件计算自动获得脉络膜平均厚度，观察并与术前比较是否有改变。结果：术前，两组视力、眼压和脉络膜厚度均无统计学差异(P>0.05)。小梁切除术后2周，合并糖尿病组脉络膜厚度比青光眼组厚，两组比较，差异具有统计学意义(P<0.05)；但两组视力与眼压均无统计学差异(P>0.05)。组内治疗前后情况，两组视力与脉络膜厚度无统计学差异(P>0.05)，但眼压在术后明显降低，差异具有统计学意义(t=10.76，P=0.00)。结论：开角型青光眼是否合并有糖尿病于小梁切除术后对脉络膜厚度无影响。
The changes of choroidal thickness in the open-angle glaucoma patients whether merge diabetes after trabeculectomy
Objective: Observe on the changes of choroidal thickness after trabeculectomy in the open-angle glaucoma (POAG) patients and the open-angle glaucoma also suffering diabetes patients. Methods: A total of 120 POAG patients (130 eyes) whom were therapied in our hospital were chose in this study. The subjects were divided into glaucoma groups (69 cases, 76 eyes) and diabetes group (51 cases, 54 eyes) according to whether merge diabetes. Measure the vertical distance between the retinal pigment epithelium and the scleral layer with OCT. The average choroidal thickness is calculated automatically by the software. The changes were observed and compared with the preoperative. Results: Preoperatively the differences of the visual acuity, intraocular pressure and choroidal thickness of the two groups were no statistically significant (P>0.05). Two weeks after trabeculectomy, the choroidal thickness of the diabetic group was thicker than the glaucoma group. The difference between the two groups were statistically significant (P<0.05). But the differences of the visual acuity and intraocular pressure were no statistically significant (P>0.05). The situation within the group before and after treatment, the differences of visual acuity and choroidal thickness were no statistically significant (P>0.05), but the intraocular pressure was decreased significantly after surgery, which was statistically significant (t=10.76, P=0.00). Conclusion: Open-angle glaucoma whether merge diabetes does not affect the thickness of the choroid after trabeculectomy.