论著 Original Article

我院2010-2014年中药注射剂致不良反应报告分析

Published at: 2015年第35卷第3期

沈颖 1 , 吴泊 1
1 江苏大学附属宜兴市人民医院,江苏 宜兴 214200
通讯作者 颖 沈 Email: 1726144687@qq.com
DOI: 10.3978/j.issn.2095-6959.10.3978/j.issn.2095-6959.2015.03.011
基金:

摘要

目的:考察中药注射剂引起的不良反应(adverse drug reactions,ADR)的发生情况,并分析其原 因,为临床合理用药提供参考。方法:对2010年1月~2014年12月收集的244例中药注射剂不良反应 报告统计结果进行分析。结果:244例不良反应中,男性137例,女性107例,60岁以上患者发生率 最高,占47.95%。引起中药注射剂不良反应构成比最高的为参麦注射液32例,占13.11%,其次为 丹红注射液(12.70%)、银杏达莫注射液(10.66%)。不良反应的临床表现主要为皮肤及其附件损害, 占23.8%。结论:熟练掌握中药注射剂的不良反应,积极应对不良反应,有利于提高中药注射剂的 合理使用水平,提高临床疗效,做到安全、合理用药。


Analysis on adverse drug reaction during 2010-2014 induced by Chinese material medical injections in our hospital

Abstract

Objective: To survey the occurrence and analyze the reason of the adverse drug reactions (ADR) of Chinese material medical injections (CMMI) and provide references for rational drug use in the clinic. Methods: 244 ADR reports induced by CMMI from January 2010 to December 2014 were statistically analyzed. Results: In all 244 cases, 137 male and 107 female patients; Elderly (>60 years) patients with a higher incidence of ADR, accounting for 47.95%. Shenmai injection had the highest ratio (32cases), accounting for 13.11% of the total ADR induced by CMMI, and the next were Danhong injection (12.70%) and Yinxingdamo injection (10.66%). Lesions of skin and its appendages were clinically common ADR, which accounted for 23.8% of the total ADR. Conclusion: It is useful to improve the level of rational usage of CMMI by mastering ADR of CMMI, so as to improve the clinical efficacy and safety and use the drugs rationally.


comments powered by Disqus

全文

引用

引用本文: 颖 沈, 泊 吴. 我院2010-2014年中药注射剂致不良反应报告分析[J]. 临床与病理杂志, 2015, 35(3): 382-387.
Cite this article as: SHEN Ying, WU Po . Analysis on adverse drug reaction during 2010-2014 induced by Chinese material medical injections in our hospital [J]. Journal of Clinical and Pathological Research, 2015, 35(3): 382-387.