Objective: To explore the imaging characteristics of patients with giant serpentine aneurysm (GSA). Methods: Continuous collected seven cases menstrual GSA patient diagnosed in our hospital or other hospitals, through CT and MRI/MRA diagnosing from March 2010 to March 2014. First we summarized the patient’s CT imaging features, then discussed them combined with the literature. Results: GSA imaging features in patients mainly as: CT scan showed lesions was not homogeneous high-density mass effect, showing the surrounding brain tissue edema and “eggshell calcification”; CT enhanced scan showed the aneurysm wall slightly strengthened, uniform strengthen relatively low density area. MRI mainly described as clear boundary, which was mixed with signal lesions, mainly for the different intensities of short T1, long T2 signal. Enhanced MRI scan showed a thick wall had significantly enhanced the tumor; no enhancement of internal thrombosis, blood flow within the channel is displayed as a high signal. CTA and MRA can be more clearly show the intracranial vascular channels and snakes out of shape. Conclusion: Imaging findings in patients with GSA has relatively specificity. CT/MRI scan can be used as an initial screening of one of its clinical and ancillary diagnostic tools.