温热疗法与10%聚维酮碘联合激光治疗复发性尖锐湿疣
| 作者: |
1毛祖豪,
1周冼苡,
1吴中,
1胡永轩,
1韩雪,
1胡燕卿,
1卢艳
1 南方医科大学第三附属医院皮肤科，广州 510630 |
| 通讯: |
吴中
Email: 503813448@qq.com |
| DOI: | 10.3978/j.issn.2095-6959.2014.04.017 |
摘要
目的：探讨温热疗法与10%聚维酮碘联合激光治疗复发性尖锐湿疣的有效性及安全性。方法：将 60例复发性尖锐湿疣患者随机分为A、B组，每组30例。A组应用温热疗法与10%聚维酮碘联合激 光治疗；B组应用激光治疗；小于1 cm疣体的复发性尖锐湿疣患者30例作为C组，应用光动力治 疗。每组观察6个月然后判定疗效。结果：A组治愈27例，复发3例；B组治愈19例，复发11例；C 组治愈26例，复发4例；A组疗效优于B组(χ2=5.963，P=0.015)；而A组与C组的疗效比较差异无统 计学意义(χ2=0.162，P=0.688)。A组治疗期间出现可耐受不良反应。结论：温热疗法与10%聚维酮 碘联合激光治疗复发性尖锐湿疣有效而安全，优于单纯激光治疗，与光动力治疗疗效相当。
关键词：
尖锐湿疣；温热疗法；聚维酮碘；激光治疗
Combination of thermotherapy with 10% povidone iodine and laser in treatment of recurrent condyloma acuminatum
CorrespondingAuthor: WU Zhong Email: 503813448@qq.com
DOI: 10.3978/j.issn.2095-6959.2014.04.017
Abstract
Objective: To investigate the efficacy and safety of the combination of thermotherapy with 10% povidone iodine and laser in treatment of recurrent condyloma acuminatum. Methods: Sixty patients with recurrent condyloma acuminatum were randomly divided into A and B groups (n=30). Group A, combination of thermotherapy with 10% povidone iodine and laser; Group B, laser treatment alone. Patients who had recurrent condyloma acuminatum with wart body diameter less than 1 cm were assigned into Group C, subjected to photodynamic therapy. Each group was observed for 6 months to determine efficacy. Results: In Group A, 27 patients were cured and 3 recurred. In Group B, 19 patients were cured and 11 recurred. In Group C, 26 patients were cured and 4 recurred. The efficacy in Group A was better than that in Group B (χ2=5.963, P=0.015), but there was no significant difference between A and C group(χ2=0.162, P=0.688). Some side effects appeared in patients in Group A during the treatment but all patients were able to tolerate them. Conclusion: The combination thermotherapy with 10% povidone iodine and laser in treatment of recurrent condyloma is effective and safe, which shows similar therapeutic effect to photodynamic treatment.