文章摘要

皮下脂肪组织与内脏脂肪组织

作者: 1刘琼, 1肖新华
1 南华大学附属第一医院内分泌科,湖南 衡阳 421001
通讯: 肖新华 Email: xiaoxinhua139@163.com
基金: 国家自然科学基金, 81070667,81270925 湖南省自然科学基金重点项目, 12JJ2050

摘要

肥胖不仅指过多的脂肪积聚,还包括脂肪的分布异常。内脏脂肪的增加是多种代谢性疾病(如2型糖尿病、心血管疾病等)的高危因素。脂肪组织通过分泌脂肪细胞因子和炎症因子调节胰岛素敏感性和参与胰岛素信号通路。因此,研究脂肪组织分布与内分泌特点对防治肥胖及其相关疾病具有重要的意义。
关键词: 皮下脂肪组织;内脏脂肪组织;脂肪分布;胰岛素抵抗

Subcutaneous and visceral adipose tissue

Authors: 1LIU Qiong, 1XIAO Xinhua
1 Department of Endocrinology, First Affiliated Hospital of University of South China, Hengyang Hunan 421001, China

CorrespondingAuthor: XIAO Xinhua Email: xiaoxinhua139@163.com

Abstract

Obesity, not only defined as excessive fat accumulation, but also implies abnormal fat distribution. The increasing visceral adipose tissue is a risk factor for multiple metabolic diseases, such as Type 2 diabetes and cardiovascular disease. Adipose tissue regulates the sensitivity of insulin and insulin signal pathway by secretion of various adipokines and inflammatory factors. Therefore, study of adipose tissue distribution and the characteristics of endocrine is of great significant in prevention and treatment of obesity and related diseases.

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