文章摘要

不同血压控制水平下妊娠期高血压孕妇母儿结局的比较

作者: 1郭美玉, 1刘庆妍, 1王坤, 1张静
1 北京积水潭医院妇产科,北京 100096
通讯: 郭美玉 Email: zzqtj123@163.com
DOI: 10.3978/j.issn.2095-6959.2020.12.020

摘要

目的:探讨比较不同血压控制水平下妊娠期高血压(gestational hypertension,GHp)孕妇母儿结局。方法:回顾性收集2015年1月至2017年12月我院收治的296例轻中度GHp孕妇临床资料,根据孕期血压控制水平(以收缩压、舒张压中较高者进行分组)将孕妇分为四组,A组(<130/80 mmHg)107例,B组[(130~139)/(80~89) mmHg]121例,C组[(140~149)/(90~99) mmHg]36例,D组[(150~159)/(100~109) mmHg]32例,比较四组重度GHp、子痫前期(PE)、PE伴蛋白尿、重度子痫前期(sPE)、小于胎龄儿发生情况及妊娠结局。结果:4组重度GHp和sPE发生率比较差异有统计学意义(P<0.05),且随着孕期血压水平增高,重度GHp和sPE发生率呈增高趋势(P<0.05);而四组PE和PE伴蛋白尿、小于胎龄儿等发生率比较差异无统计学意义(P>0.05)。Logistic回归分析显示,孕期血压水平是轻中度GHp孕妇发生重度GHp的影响因素(P<0.05);且孕期血压水平是轻中度GHp孕妇发生sPE的影响因素(P<0.05);4组孕妇早产、产后出血、新生儿Apgar评分、新生儿窒息发生率比较差异有统计学意义(P<0.05),并随孕妇血压水平上升其早产、产后出血、新生儿Apgar评分、新生儿窒息有增加或降低。结论:孕妇血压水平可影响母婴结局,积极控制轻中度GHp孕妇血压水平,有助于减少重度GHp和sPE发生。
关键词: 妊娠期高血压;血压水平;母儿结局

Comparison of maternal and neonatal outcomes of pregnant women with gestational hypertension among different blood pressure control levels

Authors: 1GUO Meiyu, 1LIU Qingyan, 1WANG Kun, 1ZHANG Jing
1 Department of Obstetrics and Gynaecology, Beijing Jishuitan Hospital, Beijing100096, China

CorrespondingAuthor: GUO Meiyu Email: zzqtj123@163.com

DOI: 10.3978/j.issn.2095-6959.2020.12.020

Abstract

Objective: To compare the maternal and neonatal outcomes of pregnant women with gestational hypertension (GHp) under different blood pressure control levels. Methods: This retrospective study was collected from a total of 296 mild to moderate GHp patients in the hospital during January 2015 to December 2017. According to the blood pressure control level during pregnancy, pregnant women with relatively higher systolic pressure and diastolic pressure were divided into group A (<130/80 mmHg, 107 cases), group B [(130–139)/(80–89) mmHg, 121 cases], group C [(140–149)/(90–99) mmHg, 36 cases] and group D [(150–159)/(100–109) mmHg, 32 cases]. The occurrence of severe GHp, preeclampsia (PE), PE with proteinuria, severe preeclampsia (sPE) and small for gestational age infants and pregnancy outcomes were compared among the four groups. Results: Differences in incidences of severe GHp and sPE among the four groups showed statistical significance (P<0.05). With the increase of blood pressure during pregnancy, incidences of severe GHp and sPE increased (P<0.05). Differences among the four groups in incidences of PE, PE with proteinuria or small for gestational age infants showed no statistical significance (P>0.05). Logistic regression analysis showed that blood pressure level during pregnancy was an independent influencing factor of severe GHp and sPE in pregnant women with mild to moderate GHp (P<0.05). Differences among the four groups in incidences of premature delivery and postpartum hemorrhage, neonatal Apgar score and incidence of neonatal asphyxia showed statistical significance (P<0.05), which changed with the blood pressure level. Conclusion: Maternal and neonatal outcomes are affected by maternal blood pressure level. Active control of the blood pressure level in pregnant women with mild to moderate GHp can help to decrease the occurrence of severe GHp and sPE.
Keywords: gestational hypertension; blood pressure level; maternal and neonatal outcomes

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