文章摘要

血小板分布宽度在恶性肿瘤中的研究进展

作者: 1王雅冬, 2史小荣
1 山西医科大学第一临床医学院,太原 030001
2 山西医科大学第一医院妇科,太原 030001
通讯: 史小荣 Email: sxrglj123456888@163.com
DOI: 10.3978/j.issn.2095-6959.2020.10.041

摘要

恶性肿瘤可以引起血小板的活化,从而使血小板黏附在肿瘤细胞上,通过一系列反应,介导恶性肿瘤的生长、侵袭及转移,还促进恶性肿瘤内血管的生长。而血小板分布宽度是血小板活化的指标之一,已有研究证实血小板分布宽度与鼻咽癌、喉癌、胃癌、乳腺癌等恶性肿瘤之间存在显著相关性,对恶性肿瘤有一定的辅助诊断及预后预测价值。
关键词: 血小板分布宽度;恶性肿瘤;血小板活化

Research progress of platelet distribution width in malignant tumors

Authors: 1WANG Yadong, 2SHI Xiaorong
1 First Clinical Medical College, First Hospital, Shanxi Medical University, Taiyuan 030001, China
2 Department of Gynecology, First Hospital, Shanxi Medical University, Taiyuan 030001, China

CorrespondingAuthor: SHI Xiaorong Email: sxrglj123456888@163.com

Abstract

Malignant tumors can lead to platelets activation, allowing platelets to adhere to tumor cells. Through a series of reactions, it mediates the growth, invasion and metastasis of malignant tumors, and also promotes the growth of blood vessels in malignant tumors. The platelet distribution width is one of the indicators of platelet activation. It has been confirmed that there is a significant correlation between platelet distribution width and malignant tumors such as nasopharyngeal carcinoma, laryngeal cancer, gastric cancer, breast cancer, etc. And it has certain auxiliary diagnosis and prognostic value for malignant tumors.
Keywords: platelet distribution width; malignant tumors; platelet activation