文章摘要

免疫相关性周围神经病研究进展

作者: 1顾美娟, 1刘彬
1 昆明医科大学第一附属医院老年神经内科,昆明 650000
通讯: 刘彬 Email: ynkmlba@126.com
DOI: 10.3978/j.issn.2095-6959.2020.11.036
基金: 云南省应用基础研究项目(201801CH00572);云南省医药卫生研究项目(2018NS0102)。

摘要

周围神经疾病病因众多,目前免疫相关性周围神经病成为研究热点。近年来各国学者针对周围神经不同组成区域(郎飞结区、结侧区、近结侧区)进行探索,从而不断发现新的抗体,对免疫介导的周围神经疾病的诊断和治疗有重要的指导意义。
关键词: 周围神经病变;免疫;抗体;临床表现;治疗

Research progress in immune-related peripheral neuropathy

Authors: 1GU Meijuan, 1LIU Bin
1 Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming 650000, China

CorrespondingAuthor: LIU Bin Email: ynkmlba@126.com

Foundation: This work was supported by the Yunnan Applied Basic Research Project-Union Foundation (201801CH00572) and Yunnan Provincial Medical Health Research Institute Project (2018NS0102), China.

Abstract

It is now apparent that immune-related peripheral neuropathy has become an important cause of acquired peripheral neuropathy.This review summarises recent antibodies involved of nodal, paranodalregion and juxtaparanodalregion, which have already begun to inform increasingly targeted and individualised therapies.
Keywords: neuropathies; immune; antibody; clinical feature; treatment