文章摘要

前庭大腺腺样囊性癌1例

作者: 1欧阳晨捷, 1周东华
1 佛山市妇幼保健院病理科,广东 佛山 528000
通讯: 周东华 Email: 494827650@qq.com
DOI: 10.3978/j.issn.2095-6959.2020.11.046

摘要

采用光镜及免疫组织化学等方法对1例前庭大腺腺样囊性癌进行临床、病理回顾性分析。本例患者以右侧外阴隐痛入院,临床初步诊断为“前庭大腺脓肿”。行会阴肿块切除术后,光镜下见肿瘤细胞小而一致,呈基底细胞样、腺样或不典型筛状排列,这些大小不等的腺腔或筛孔内见分泌的黏液或红染均质的圆柱状物,伴多量神经束侵犯,浸润肌肉组织,免疫组织化学表达腺上皮及肌上皮标志。前庭大腺腺样囊性癌是发生在女性外阴非常罕见的恶性肿瘤,临床诊断困难,明确诊断需要病理活检及免疫组织化学检测。
关键词: 外阴;前庭大腺;腺样囊性癌;病理;诊断

Clinicopathologic analysis of adenoid cystic carcinoma of Bartholin’s gland: A case report

Authors: 1OUYANG Chenjie, 1ZHOU Donghua
1 Department of Pathology, Foshan Women and Children Hospital, Foshan Guangdong 528000, China

CorrespondingAuthor: ZHOU Donghua Email: 494827650@qq.com

Abstract

The clinical characteristics and the microscopic and immunohistochemical characteristics of a case with adenoid cystic carcinoma of Bartholin’s gland were analyzed with a follow-up period. Related literature was reviewed.The case was found with a right vulva pain,and was clinically diagnosed as Bartholin’s gland abscess. But under the light microscope, the following can be seen in the patient’s removed perineal mass. The tumor cells are small and uniform, arranged in a basal cell-like, adenoid or atypical sieving pattern. The secreted mucus or red-stained homogeneous cylindrical body can be seen in these glands or meshes of different sizes. In addition, scattered tumor cells are also found in nerve tissues and peripheral muscle tissues. Its immunohistochemical markers are glandular epithelial and myoepithelial positivity. Adenoid cystic carcinoma of Bartholin’s gland is a very rare malignant tumor that occurs in female vulva. Therefore, in addition to clinical diagnosis, pathological biopsy and immunohistochemical detection are required to confirm the diagnosis.
Keywords: vulva; Bartholin’s gland; adenoid cystic carcinoma; pathology; diagnosis