文章摘要

性发育异常患者的性腺组织病理学的研究进展

作者: 1蔡永川, 2毛宇, 1,2唐耘熳
1 遵义医科大学研究生院,贵州 遵义 563000
2 四川省人民医院儿童医学中心,成都 610072
通讯: 唐耘熳 Email: tangyunman@126.com
DOI: 10.3978/j.issn.2095-6959.2021.05.029
基金: 四川省卫生与计划生育委员会科研基金(150206)。

摘要

性发育异常疾病(disorders of sex development,DSD)患者性腺的发育程度与患者的性腺癌变风险、性别选择、手术方案、性激素水平等密切相关。但关于DSD性腺的组织病理学特点及其与DSD临床诊治之间的联系、性腺发育异常的调控机制、性腺癌变的监测等研究仍不够完善。
关键词: 性发育异常;性腺;组织病理学;癌变

Research progress of gonadal histopathology in patients with disorders of sex development

Authors: 1CAI Yongchuan, 2MAO Yu, 1,2TANG Yunman
1 Graduate School, Zunyi Medical University, Zunyi Guizhou 563000, China
2 Children’s Medical Centre, Sichuan Provincial People’s Hospital, Chengdu 610072, China

CorrespondingAuthor: TANG Yunman Email: tangyunman@126.com

DOI: 10.3978/j.issn.2095-6959.2021.05.029

Foundation: This work was supported by the Scientific Research Fund Project of Sichuan Provincial Health and Family Planning Commission, China (150206).

Abstract

The degree of gonadal development in patients with DSD is closely related to the risk of gonadal carcinogenesis, sex selection, surgical plan, sex hormone levels, etc. However, studies on the histopathological characteristics of gonad in patients with DSD and its relationship with clinical diagnosis and treatment, the regulation mechanism of gonadal dysplasia, and the monitoring of gonadal carcinogenesis are far from perfect.
Keywords: disorders of sex development; gonadal; histopathology; carcinogenesis

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