文章摘要

中医药治疗活动期溃疡性结肠炎的用药规律

作者: 1,2潘琪谋, 1,2郑欢, 1,2李间清, 1,2黄绍刚
1 省部共建中医湿证国家重点实验室(广州中医药大学第二附属医院),广州 510006
2 广东省中医院杨春波学术经验传承工作室,广州 510006
通讯: 黄绍刚 Email: huangshaogang@126.com
DOI: 10.3978/j.issn.2095-6959.2020.09.022
基金: 广州中医药大学学科研究重点项目(XK-2019027);全国中医药创新骨干人才培训项目[国中医药人教函(2019)128号];省部共建中医湿证国家重点实验室专项[中医二院(2020)20号]

摘要

目的:研究中药在治疗活动期溃疡性结肠炎中的使用规律。方法:研究对象取2016年1月至2019年3月在广东省中医院治疗的活动期溃疡性结肠炎患者124人次,总结不同证候的比例,探究中药在不同证候及总体患者中的使用规律。结果:中药治疗溃疡性结肠炎使用频率最高的药物依次为甘草、黄连、白芍、白术、黄芩、茯苓、当归等;性味上,温性最高,凉性次之,苦味最高,甘味次之;归经上,入脾经最高,胃经次之;药物分类上,补虚药最高,清热药次之。结论:中药治疗溃疡性结肠炎用药有一定规律性,但尚缺乏更进一步的临床研究对其有效性进行统计验证。
关键词: 溃疡性结肠炎;证候规律;中药;用药规律

Regularity of drug use in the treatment of active ulcerative colitis with traditional Chinese medicine

Authors: 1,2PAN Qimou, 1,2ZHENG Huan, 1,2LI Jianqing, 1,2HUANG Shaogang
1 Laboratory of Damp Syndrome Jointly of Traditional Chinese Medicine Established by the Province and the Ministry (Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou 510006, China
2 Yang Chunbo Academic Experience Inheritance Studio, Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510006, China

CorrespondingAuthor: HUANG Shaogang Email: huangshaogang@126.com

Foundation: This work was supported by the Key Research Projects of Guangzhou University of Traditional Chinese Medicine (XK-2019027), the National Training Program for Innovative Backbone Talents of Traditional Chinese Medicine [Guozhongyiyao Renjiaohan (2019)No. 128], and the State Key Laboratory Special Subject of Dampness Syndrome of Chinese Medicine [Zhongyi Eryuan (2020) No.20], China.

Abstract

Objective: To study the rule of using traditional Chinese medicine in the treatment of active ulcerative colitis. Methods: A total of 124 patients with active ulcerative colitis in Guangdong Provincial Hospital of Chinese Medicine from January 2016 to March 2019 were selected. The proportion of different syndromes was summarized, and the rule of using traditional Chinese medicine in different syndromes and patients was explored. Results: The most frequently used drugs in the treatment of ulcerative colitis were liquorice, Coptis chinensis, Paeonia lactiflora, baizhu, Poria cocos, angelica, etc. In flavor and meridian tropism warm syndrome is the most commonly used and cooler syndrome is the second one. Bitter ranks first and sweet follows. In meridian tropism, the spleen meridian is the highest, followed by the stomach meridian; in drug classification, the tonifying deficiency medicine is the highest, followed by the heat-clearing medicine. Conclusion: There is a certain regularity in the use of traditional Chinese medicine for ulcerative colitis, but there is still a lack of further clinical studies to verify its effectiveness.
Keywords: ulcerative colitis; syndrome regularity; traditional Chinese medicine; drug use regularity