文章摘要

乳腺组织标记定位针在乳腺癌新辅助化疗后保乳手术中的应用

作者: 1郝军生, 1李南林
1 空军军医大学第一附属医院甲乳血管外科,西安 710032
通讯: 李南林 Email: nanlin-74@163.com
DOI: 10.3978/j.issn.2095-6959.2020.09.015

摘要

目的:探讨乳腺组织标记定位针(靶钉)对可手术乳腺癌保乳率的影响。方法:回顾性分析自靶钉置入技术开展以来13例可手术乳腺癌病例,化疗期间于癌灶内通过超声引导置入靶钉,对足疗程新辅助化疗后进行保乳切除手术的保乳手术实施情况,分析化疗后的病理完全缓解(pathological complete response,pCR)率及术后局部复发和远处转移情况,对比靶钉置入前后对乳腺癌保乳手术率的影响。结果:13例靶钉置入的乳腺癌患者均足疗程完成了新辅助化疗,其中10例完成了保乳手术,保乳率达76.9%(10/13),较靶钉置入技术开展前2017年的保乳手术率26.31%(226/859)明显提高。术后中位随访4个月(2~19个月,38.5%随访10个月以上)无局部复发和远处转移。结论:靶钉置入有利于提高新辅助化疗后乳腺癌的保乳手术率。
关键词: 乳腺组织标记定位针;新辅助化疗;保乳手术

Application of ultra clip dual trigger breast tissue marker in breast conserving surgery after the neoadjuvant treatment

Authors: 1HAO Junsheng, 1LI Nanlin
1 Department of Thyroid, Breast and Vascular Surgery, First Hospital Affiliated to Air-Force Medical University, Xi’an 710032, China

CorrespondingAuthor: LI Nanlin Email: nanlin-74@163.com

Abstract

Objective: To investigate the effect of breast tissue markers (target nail) on breast-conserving rate of operable breast cancer. Methods: A retrospective analysis of 13 cases of operable breast cancer since the introduction of target nail placement technology was performed. During chemotherapy, each patient placed a target nail in a breast cancer lesion under ultrasound guidance. Breast-conserving surgery rate, pathological complete response (pCR) rate after neoadjuvant chemotherapy, and the postoperative local recurrence and distant metastasis were analyzed. Breast-conserving surgery rate before and after target nail placement technology was compared. Results: All 13 breast cancer patients with target nail placement completed neoadjuvant chemotherapy, and 10 of them completed breast-conserving surgery with a breast-conservation rate of 76.9% (10/13). The rate of breast-conserving surgery in 2017 was 26.31% (226/859). The median follow-up was 4 months (2–19 months, 38.5% more than 10 months) without local recurrence and distant metastasis. Conclusion: Target nail placement is beneficial to improve breast-conserving surgery rate of breast cancer after neoadjuvant chemotherapy.
Keywords: ultra clip dual trigger breast tissue marker; neoadjuvant chemotherapy; breast conserving surgery