文章摘要

猪小肠及系膜损伤的生物力学研究

作者: 1刘畅, 2周航, 1杨幼林
1 哈尔滨医科大学附属第一医院消化内科,哈尔滨 150001
2 黑龙江省医院消化内科,哈尔滨 150036
通讯: 杨幼林 Email: yangyoulinyyl@163.com
DOI: 10.3978/j.issn.2095-6959.2020.09.004

摘要

目的:利用猪小肠及系膜,探究成襻时小肠及系膜可承受最大拉力。方法:选取不同长度的猪小肠及系膜,应用半圆硬质弯杆替代小肠镜模拟肠管成襻,采用推拉力计测量小肠壁及系膜能承受的最大拉力。结果:牵拉力逐渐增加时,肠系膜最先受损。肠系膜能承受的最大牵拉力与肠管长度呈正相关(r=0.932,P<0.001),猪小肠系膜能承受的最大牵拉力(y)与肠管长度(x)的回归方程:y=2.205x+13.732。结论:当小肠成襻时,即使没有肠壁损伤,肠系膜撕裂也可能发生。形成的肠襻越大,系膜所能承受的牵拉力越大。这些结果可以指导小肠镜的操作。
关键词: 小肠镜;组织损伤;破坏负荷

Biomechanical study on small bowel and mesenteric injuries of pigs

Authors: 1LIU Chang, 2ZHOU Hang, 1YANG Youlin
1 Department of Gastroenterology, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
2 Department of Gastroenterology, Heilongjiang Provincial Hospital, Harbin 150036, China

CorrespondingAuthor: YANG Youlin Email: yangyoulinyyl@163.com

Abstract

Objective: To analyze the tolerance of mesentery and small bowel when loops were formed via using the samples of pigs. Methods: Porcine mesentery and small bowel of different lengths were subjected to tensile tests. Semicircular steel rods were used to replace enteroscope to simulate the loop formation. Tensiometer was to measure the maximum tensile force that the mesentery and small bowel could bear. Results: The mesentery was the first to be damaged when the pulling force increased. There was a positive linear correlation between the maximum pulling force and the length of the loop (r=0.932, P<0.001). The regression equation between the maximum pulling force that the porcine mesentery can bear (y) and the length of the loop(x) is y=2.205x+13.732. Conclusion: When the small bowel becomes a loop, mesenteric tear may occur even if there is no small bowel damage. The greater the loop is, the greater pulling force the mesentery can withstand. These results can guide the operation of enteroscopy.
Keywords: small intestinal endoscopy; tissue damage; failure load