文章摘要

卵巢癌肉瘤伴神经内分泌分化1例并文献复习

作者: 1王 金文, 1杨 珍玉, 1黄 美园, 1陈 栋良
1 中南大学湘雅医学院附属株洲医院病理科,湖南 株洲 412007
通讯: 陈 栋良 Email: 1156080708@qq.com
DOI: 10.3978/j.issn.2095-6959.2020.04.042
基金: 株洲市2018年度科技指导性计划项目(201807)。

摘要

卵巢癌肉瘤(ovarian carcinosarcoma,OCS)是较为罕见的女性生殖道恶性肿瘤,该病预后极差。尽管有较多经典成分类型的OCS病例报道,但目前国内尚未见伴有神经内分泌分化(neuroendocrine differentiation,NED)的OCS相关报道。现报道中南大学湘雅医学院附属株洲医院的1例患者,48岁,女性,因腹部增大8个月入院,影像学提示卵巢囊性癌,病理结果示右侧OCS伴NED,左侧卵巢浆液性乳头状囊腺癌。患者行彻底的卵巢肿瘤减灭术和辅助化疗,随访8个月为无病生存状态且未见复发。
关键词: 卵巢癌肉瘤;神经内分泌分化;预后

Ovarian carcinosarcoma with neuroendocrine differentiation: A case report and literature review

Authors: 1WANG Jinwen, 1YANG Zhenyu, 1HUANG Meiyuan, 1CHEN Dongliang
1 Department of Pathology, Affiliated Zhuzhou Hospital Xiangya Medical College CSU, Zhuzhou Hunan 412007, China

CorrespondingAuthor:CHEN Dongliang Email: 1156080708@qq.com

Foundation: This work was supported by Zhuzhou Science and Technology Guidance Plan Project, China (201807).

Abstract

Ovarian carcinosarcoma is a rare tumor with a grim prognosis among gynaecological tumors. Although several canonical components have been described in ovarian carcinosarcomas, ovarian carcinosarcomas with neuroendocrine differentiation (NED) has not been reported in the Chinese literature. To raise awareness of the histological type in this tumor, we present a 48-year-old woman who admitted to the hospital with self-check increasing circumference of abdomen for 8 months gradually. CT imaging gave a cue that she might have ovarian cystic carcinoma. Pathological examination showed right ovarian carcinosarcoma with NED, and left ovary was plasma papillary carcinoma. She underwent completely ovarian tumor reduction surgery and adjuvant chemotherapy. The patient had been free of the disease and showed no evidence of recurrence 8 months after the operation.
Keywords: ovarian carcinosarcoma; neuroendocrine differentiation; prognosis