文章摘要

维生素AD联合铁剂治疗婴幼儿缺铁性贫血的效果

作者: 1张 海艳, 2唐 朝亮, 1宋 文仕, 1杨 龑
1 庐江县人民医院儿科,合肥 231500
2 中国科学技术大学附属第一医院麻醉科,合肥 230001
通讯: 宋 文仕 Email: 1641450305@qq.com
DOI: 10.3978/j.issn.2095-6959.2020.04.012
基金: 国家卫生与计划生育委员会医药卫生科技发展研究中心(W2016EWAH20);国家自然科学基金(81801175);中央高校基本科研业务费专项资金(WK9110000044)。

摘要

目的:观察维生素AD滴剂联合蛋白琥珀酸铁口服液治疗婴幼儿缺铁性贫血的临床效果。方法:选取安徽省庐江县人民医院儿童保健门诊缺铁性贫血患儿102例,性别不限,采用随机数字表法分为观察组(n=52)和对照组(n=50)。观察组治疗采用蛋白琥珀酸铁口服液联合维生素AD滴剂口服,对照组治疗仅采用蛋白琥珀酸铁口服液口服。治疗前分析缺铁性贫血患儿维生素A和25-羟维生素D缺乏情况,于治疗1个月后对2组治疗效果进行比较并对贫血相关指标进行分析。结果:治疗前两组缺铁性贫血患儿维生素A和25-羟维生素D缺乏严重。治疗后,观察组的显效率为61.54%,明显高于对照组的44%(P<0.05);总有效率为94.23%,也明显高于对照组的84%(P<0.05);观察组血红蛋白、血清铁和血清铁蛋白较对照组明显改善(P<0.05)。结论:维生素AD滴剂联合蛋白琥珀酸铁口服液用于婴幼儿缺铁性贫血治疗时可有效改善患儿相关的贫血指标,显著提高临床治疗效果。
关键词: 婴幼儿;缺铁性贫血;维生素AD滴剂;蛋白琥珀酸铁口服液

Effect of vitamin AD combined with iron in infants with iron deficiency anemia

Authors: 1ZHANG Haiyan, 2TANG Chaoliang, 1SONG Wenshi, 1YANG Yan
1 Department of Pediatrics, Lujiang General Hospital, Hefei 231500, China
2 Department of Anesthesiology, First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China

CorrespondingAuthor:SONG Wenshi Email: 1641450305@qq.com

Foundation: This work was supported by the National Health and Family Planning Commission Medical and Health Technology Development Research Center (W2016EWAH20), National Natural Science Foundation (81801175), and Fundamental Research Funds for the Central Universities (WK9110000044), China.

Abstract

Objective: To observe the clinical effect of vitamin AD drops combined with iron proteinsuccinylate oral solution in the treatment of iron deficiency anemia in infants. Methods: A total of 102 children of both sexes with iron deficiency anemia in our children’s health clinic were equally and randomly allocated into an observation group (n=52) and a control group (n=50). The observation group was treated with iron proteinsuccinylate oral solution combined with vitamin AD drops orally, and the control group was just treated with iron proteinsuccinylate oral solution orally. Before the treatment, the serum vitamin A and 25-hydroxyvitamin D deficiency in children with iron deficiency anemia were analyzed. The treatment effects were compared and the anemia related indicators were also analyzed and compared between the 2 groups 1 month after the treatment. Results: Serum vitamin A and 25-hydroxyvitamin D deficiency were serious lack in children with iron deficiency anemia before the treatment. After the treatment, the treatment effective rate of the observation group was 61.54%, which was significantly higher than that of the control group (44%) (P<0.05); the total treatment effective rate was 94.23%, which was also significantly higher than the control group (84%) (P<0.05). Hemoglobin, serum iron and serum ferritin were significantly improved compared with the control group (P<0.05). Conclusion: Vitamin AD drops combined with iron proteinsuccinylate oral solution for the treatment of iron deficiency anemia in infants can effectively improve the anemia indicators associated and significantly improve the efficiency of clinical treatment.
Keywords: infants and young children; iron deficiency anemia; vitamin AD drops; iron proteinsuccinylate oral solution