上尿路尿路上皮癌预后分子的研究进展
| 作者: |
1吴西抗,
1贺慧颖
1 北京大学医学部病理系/北京大学第三医院病理科，北京 100083 |
| 通讯: |
贺慧颖
Email: huiyinghe@bjmu.edu.cn |
| DOI: | 10.3978/j.issn.2095-6959.2020.03.031 |
摘要
上尿路尿路上皮癌(upper tract urothelial carcinoma，UTUC)是一种在西方国家相对少见的肿瘤，约占尿路上皮癌的5%，而UTUC在中国的发病率远高于西方国家。近年来对UTUC预后分子的研究有较大的进展，包括Ki-67，P53和HER-2等在肿瘤病理实践中被广泛应用的分子，还有不少有应用前景的膜受体和信号转导分子，以及一些近期较热门的分子，如PD-1和PDL-1等。
关键词：
上尿路尿路上皮癌；肿瘤进展；预后分子
Advances in prognostic molecules of upper tract urothelial carcinoma
CorrespondingAuthor: HE Huiying Email: huiyinghe@bjmu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2020.03.031
Abstract
Upper tract urothelial carcinoma (UTUC) is a relatively rare tumor in western countries, accounting for 5% of urothelial carcinoma, while the incidence of UTUC in China is much higher than that in western countries. In recent years, great progress has been made in the study of prognostic molecular of UTUC, including Ki-67, P53 and HER-2, which are widely used in pathological practice, as well as many promising membrane receptors, signal transduction molecules, and some popular molecules, such as PD-1 and PD-L1.
Keywords：
upper tract urothelial carcinoma; tumor progression; prognostic factors