文章摘要

糖尿病血糖控制情况与远期并发症评估的新指标

作者: 1韩 敬, 2,3陶 月红
1 大连医科大学,辽宁 大连 116044
2 扬州大学临床医学院,江苏 扬州 225001
3 江苏省苏北人民医院儿科,江苏 扬州 225001
通讯: 陶 月红 Email: ektyh520@163.com
DOI: 10.3978/j.issn.2095-6959.2020.02.034
基金: 江苏省妇幼保健协会科研项目(FYX201716)。

摘要

随着胰岛素泵、动态血糖监测系统在糖尿病治疗管理中的应用增多及对糖尿病并发症机制的不断深入研究,血糖波动、代谢记忆、晚期糖基化终产物、胞外体介导传递的精氨酸酶、miRNA在糖尿病并发症发生和发展中的作用逐渐成为关注焦点,晚期糖基化终产物、精氨酸酶和miRNA可能成为评估糖尿病远期并发症的新指标。
关键词: 糖尿病;血糖变异性;晚期糖基化终产物;精氨酸酶1;miRNA;胞外体

New indexes of blood glucose control and long-term complication evaluation in diabetes mellitus

Authors: 1HAN Jing, 2,3TAO Yuehong
1 Dalian Medical University, Dalian Liaoning 116044, China
2 Clinical Medical College, Yangzhou University, Yangzhou Jiangsu 225001, China
3 Department of Pediatrics, Northern Jiangsu People’s Hospital, Yangzhou Jiangsu 225001, China

CorrespondingAuthor:TAO Yuehong Email: ektyh520@163.com

Foundation: This work was supported by the Research Project of Jiangsu Maternal and Child Health Care Association, China (FYX201716).

Abstract

With increased using of insulin pump and continuous blood sugar monitoring system application in diabetes management, and with the deepening about the study of diabetes complications mechanism, it gradually becomes the focus on the blood sugar fluctuation, metabolic memory, advanced glycosylation end products, outside body secretion mediated transfer arginase, microRNAs in the development of diabetes complications, advanced glycosylation end products, arginase 1, and miRNA could be a new marker for the evaluation of diabetes complications.
Keywords: diabetes; blood sugar fluctuation; advanced glycosylation end products; arginase 1; miRNA; exosomes