文章摘要

内含脑膜瘤/脑膜增殖成分的儿童睾丸畸胎瘤1例

作者: 1方 园, 1王 一真
1 安徽省儿童医院病理科,合肥 230051
通讯: 方 园 Email: 522656049@qq.com
DOI: 10.3978/j.issn.2095-6959.2020.01.038

摘要

内含脑膜瘤/脑膜增殖成分的睾丸畸胎瘤非常罕见。组织学上除分化成熟的成分外,还包含与周围神经节及神经胶质相邻的脑膜瘤/脑膜增殖区域。免疫组织化学显示瘤细胞SSTR2A和PR强阳性、EMA弱阳性。临床确诊需结合组织学观察和免疫组织化学检测。
关键词: 睾丸畸胎瘤;脑膜瘤/脑膜增殖;儿童

Testicular teratoma with meningothelial proliferation: A case report

Authors: 1FANG Yuan, 1WANG Yizhen
1 Department of Pathology, Anhui Provincial Children’s Hospital, Hefei 230051, China

CorrespondingAuthor:FANG Yuan Email: 522656049@qq.com

Abstract

Meningothelial proliferation in teratoma of the testis is rare and occurs in adults. Beside the well-differentiated components, the testicular teratoma contained a focal area of meningeal proliferative cells adjacent to peripheral nerve and glial elements. Immunohistochemically, these cells were strongly positive for somatostatin receptor 2A (SSTR2A) and progesterone receptor (PR), while weakly positive for epithelial membrane antigen (EMA). It should be paid attention to diagnosing and differentiating the lesion from morphological mimics and metastatic meningiomas.
Keywords: testicular teratoma; meningothelial proliferation; pediatrics