This article aimed to investigate the clinical manifestations, gross morphology, microscopic morphology and immunohistochemical features of gastric glomus tumors. Two cases of gastric glomus tumors were examined by gastroscopy, HE staining and immunohistochemistry staining, special dyeing. The clinical manifestations, microscopic morphology and immunohistochemical characteristics were observed, and related literatures were reviewed. One male of 2 patients showed a circular bulge with a diameter of about 2 cm on the surface of the gastric mucosa, the surface was smooth and a female, gastroscopic examination showed a circular bulge with a diameter of about 3 cm on the surface of the gastric mucosa, the surface was smooth. Both patients had symptoms of upper abdominal pain before admission. Under light microscopy, the tumor tissue showed nodular lobular shape and was surrounded by smooth muscle cells. The tumor cells are uniform in size and round or oval. They are arranged around the thin-walled blood vessels or around the sinusoids. They are angiocarcinoma-like or solid nest-like, and the nucleus of the tumor is round. Immunohistochemical Vimentin, SMA, Calponin and type IV collagen were all positive, and the remaining CD117, DOG-1, CD34, CKAE1/AE3, Syn and S100 were negative. PAS staining showed that both cases of gastric glomus tumors, the mesenchyme showed a fine branch-like distribution between cells, and some areas showed chicken-like changes. Most of the glomus tumors of the stomach are benign tumors, which need to be confirmed by histopathology and immunohistochemistry.