文章摘要

氢气对慢性阻塞性肺疾病保护机制的研究进展

作者: 1郝 立姣, 1李 靖, 1张 志华, 1王 润钰, 1赵 一茹, 2赵 卉
1 山西医科大学第二临床医学院,太原 030001
2 山西医科大学第二医院呼吸与危重症医学科,太原 030001
通讯: 赵 卉 Email: hui_zhao@sxmu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2019.09.032
基金: 2017年山西省卫生和计划生育委员会科研课题(2017067);山西医科大学第二医院医疗新技术项目(201707)。

摘要

慢性阻塞性肺疾病是全球范围内的公共卫生挑战,同时也是慢性病患病和病死的主要死亡原因。目前的治疗原则主要为戒烟及以支气管扩张剂为主的药物治疗,肺康复治疗亦可改善症状和生活质量,但总体疗效并不理想。氢气治疗作为一种新的医学干预方法,受到越来越多的关注,近几年已开始应用于呼吸系统疾病。
关键词: 慢性阻塞性肺疾病;氢气;抗炎;抗氧化;抗凋亡

Research progress in the protective mechanism of hydrogen on chronic obstructive pulmonary disease

Authors: 1HAO Lijiao, 1LI Jing, 1ZHANG Zhihua, 1WANG Runyu, 1ZHAO Yiru, 2ZHAO Hui
1 Second Clinical Medical College, Shanxi Medical University, Taiyuan 030001, China
2 Pulmonary and Critical Care Medicine, Second Hospital, Shanxi Medical University, Taiyuan 030001, China

CorrespondingAuthor:ZHAO Hui Email: hui_zhao@sxmu.edu.cn

Foundation: This work was supported by the 2017 Shanxi Provincial Health and Family Planning Commission Research Project (2017067) and New Medical Technology Project in the second Hospital of Shanxi Medical University (201707), China.

Abstract

Chronic obstructive pulmonary disease is a public health challenge worldwide and a leading cause of death in chronic diseases and deaths. The current treatment principles are mainly smoking cessation and bronchodilator-based drugs. Pulmonary rehabilitation can also improve symptoms and quality of life, but the overall effect is not satisfactory. As a new medical intervention method, hydrogen therapy has received more and more attention and has been applied to respiratory diseases in recent years.
Keywords: chronic obstructive pulmonary disease; hydrogen; anti-inflammation; anti-oxidation; anti-apoptosis