文章摘要

间质性膀胱炎/膀胱疼痛综合征发病机制及相关危险因素

作者: 1蔡国钢, 1周泽禹, 1谢群
1 暨南大学附属珠海医院泌尿外科,广东 珠海 519000
通讯: 谢群 Email: xqwjf@126.com
DOI: 10.3978/j.issn.2095-6959.2019.06.025

摘要

间质性膀胱炎/膀胱疼痛综合征(interstitial cystitis/bladder pain syndrome,IC/BPS)是一种慢性症状的综合,表现为膀胱急迫性、尿频、疼痛等症状。对于其病因还没有达成一致意见,目前国内外学者阐述了多种病因和发病机制,但对IC/BPS仍然通过排除诊断。研究表明,IC/BPS严重损害患者的生活质量,导致其工作时间过长、抑郁和性功能障碍。IC/BPS目前还没有明确的治疗方法,本文旨在进行IC/BPS发病机制及相关危险因素探讨的基础上,为疾病防治提供相关理论依据。
关键词: 间质性膀胱炎;膀胱疼痛综合征;发病机制;相关危险因素

Pathogenesis and relevant risk factors of interstitial cystitis/bladder pain syndrome

Authors: 1CAI Guogang, 1ZHOU Zeyu, 1XIE Qun
1 Department of Urology, Zhuhai Hospital Affiliated with Jinan University, Zhuhai Guangdong 519000, China

CorrespondingAuthor: XIE Qun Email: xqwjf@126.com

DOI: 10.3978/j.issn.2095-6959.2019.06.025

Abstract

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a complex of chronic symptoms, manifested by bladder urgency, frequency of urination, pain and other symptoms. There is no consensus on their etiology. At present, domestic and overseas scholars have elaborated on a variety of etiology and pathogenesis, but this is still through exclusion of diagnosis. There is ample evidence that IC/BPS severely impairs the quality of life of patients, leading to excessive working hours, depression and sexual dysfunction. Since there is no clear treatment method for IC/BPS, this review aims to provide a theoretical basis for prevention and treatment based on the investigation of the pathogenesis and related risk factors of them.
Keywords: interstitial cystitis; bladder pain syndrome; pathogenesis; related risk factors

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