额骨Rosai-Dorfman病1例并文献复习
| 作者: |
1丘木水,
1于晓洁,
1武净净,
1刘纬驰,
1郑杰,
1张舵
1 吉林大学第一医院整形美容外科，长春 130021 |
| 通讯: |
张舵
Email: zhangduo2002@hotmail.com |
| DOI: | 10.3978/j.issn.2095-6959.2018.01.037 |
摘要
对1例额骨Rosai-Dorfman病(Rosai-Dorfman disease，RDD)进行病理学观察及免疫组织化学分析，并复习相关文献。病理检查可见组织细胞吞噬淋巴细胞、浆细胞、红细胞或中性粒细胞；免疫组织化学示：S-100蛋白阳性，CD68阳性，CD1a阴性。额骨RDD除头皮及额部麻木外缺乏特异性临床表现，确诊有赖于病理学检查，早期手术切除病灶预后良好。
关键词：
Rosai-Dorfman病；骨；诊断；治疗
Rosai-Dorfman disease of frontal bone: A case report and literature review
CorrespondingAuthor: ZHANG Duo Email: zhangduo2002@hotmail.com
DOI: 10.3978/j.issn.2095-6959.2018.01.037
Abstract
A case of Rosai-Dorfman disease (RDD) of frontal bone was treated with clinical pathological analysis and immunohistochemistry, and literatures were reviewed. Histopathologically, the disease demonstrated that histiocytes phagocytized lymphocytes, plasma cells, erythrocytes, or polymorphonuclear leukocytes; immunohistochemical analysis demonstrated that S-100 protein and CD68 were positive, CD1a was negative. RDD of frontal bone is lack of specific clinical manifestations but numbness of the scalp and forehead. The diagnosis depends on pathological examination. Early surgical resection of the lesion has a good prognosis.
Keywords：
Rosai-Dorfman disease; bone; diagnosis; treatment