文章摘要

胶原vitrigel膜的研究进展

作者: 1徐文雅, 2周洪伟
1 涟水县人民医院门诊部,江苏 淮安 223400
2 涟水县人民医院眼科,江苏 淮安 223400
通讯: 周洪伟 Email: zhouhongwei@sjtu.org
DOI: 10.3978/j.issn.2095-6959.2018.01.034
基金: 淮安市科技局自然科学研究计划(HAB201738)。

摘要

胶原vitrigel膜是一种由I型胶原经凝胶化、玻璃化、水化制成的新生物材料,可应用于角膜组织培养、角膜细胞培养,在动物实验中可用于角膜内皮移植,还可用于眼表损伤、皮肤缺损、骨缺损的治疗。胶原vitrigel膜来源相对不受限,有希望在角膜热烧伤的治疗、组织工程角膜制作及成分移植中发挥作用。
关键词: 胶原vitrigel膜;眼表损伤;组织工程角膜

Research progress in collagen vitrigel membrane

Authors: 1XU Wenya, 2ZHOU Hongwei
1 Department of Outpatient, Lianshui County People’s Hospital, Huaian Jiangsu 223400, China
2 Department of Ophthalmology, Lianshui County People’s Hospital, Huaian Jiangsu 223400, China

CorrespondingAuthor: ZHOU Hongwei Email: zhouhongwei@sjtu.org

DOI: 10.3978/j.issn.2095-6959.2018.01.034

Foundation: This work was supported by Huaian Natural Science Research Project , China (HAB201738).

Abstract

Collagen vitrigel membrane is a new biological material which is made up of I type collagen by the steps of gelation, vitrification and hydration. It can be used for corneal tissue culture, corneal cell culture and corneal endothelial transplantation. It also can be used for ocular surface injury, skin defect and bone defect treatment in animal experiments. The collagen vitrigel membrane source is relatively unrestricted, and collagen vitrigel membranes are expected to play a role in corneal thermal burn therapy, tissue engineered cornea production and component transplantation.
Keywords: collagen vitrigel membrane; ocular surface injury; tissue engineered cornea

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